2022-07-14 21:57:10来源:医脉通阅读:10次
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2022年国际肺癌研究协会(IASLC)世界肺癌大会(WCLC)将于2022 年8月6日至9日将以线下+线上的形式举办。WCLC是肺癌领域的年度盛典,每年都会有众多重磅研究结果公布并由此更新临床实践。为此,医脉通特梳理了今年WCLC大会上值得关注的相关重磅研究进展,在WCLC开幕之前,让我们先睹为快!
摘要号:PL03.09
IMpower010:Overall Survival Interim Analysis of a Phase III Study of Atezolizumab vs Best Supportive Care in Resected
III 期研究IMpower010:
专场:全体大会,N/A
报告人:ENRIQUETA FELIP
时间地点:08:30-10:20 8/08/2022 Location: Hall C1
摘要号:PL03.12
Progression Free Survival and Overall Survival in NADIM II Study
NADIM II 研究:无进展生存期(PFS)和OS结果
专场:全体大会,N/A
报告人:Mariano Provencio
时间地点:08:30 - 10:20 8/08/2022 Location: Hall C1
摘要号:OA02.03
Tumor Bulk-RNA Seq Identifies Patients at High Risk of Progression in Non-complete Pathological Responders from NADIM Trial
肿瘤Bulk-RNA Seq检测可识别 NADIM 试验中非完全病理反应者高进展风险患者
专场:口头报告,局部晚期NSCLC
报告人:Marta Casarrubios
时间地点:12:02 - 12:12 8/07/2022 Location: Strauss 1/2
摘要号:OA02.05
Sugemalimab vs Placebo after cCRT or sCRT in pts with Unresectable Stage III NSCLC: Final PFS Analysis of a Phase 3 Study
cCRT 或 sCRT 序贯舒格利单抗对比安慰剂治疗不可切除的 III 期 NSCLC 患者的结果:III 期研究最终 PFS 分析
专场:口头报告,局部晚期NSCLC
报告人:
时间地点:12:22 - 12:32 8/07/2022 Location: Strauss 1/2
摘要号:OA03.03
Sotorasib in Combination with RMC-4630, a SHP2 Inhibitor, in KRAS p.G12C-Mutated NSCLC and Other Solid Tumors
Sotorasib 联合 SHP2 抑制剂 RMC-4630 治疗 KRAS p.G12C 突变NSCLC 和其他实体瘤的结果
专场:口头报告,转移性NSCLC-分子靶向治疗
报告人:Gerald Falchook
时间地点:14:32 - 14:42 8/07/2022 Location: Strauss 1/2
摘要号:OA03.04
Phase I A Study to Evaluate GDC-6036 Monotherapy in Patients with Non-small Cell Lung Cancer (NSCLC) with KRAS G12C Mutation
GDC-6036 单药治疗 KRAS G12C 突变NSCLC 患者的 IA 期研究结果
专场:口头报告,转移性NSCLC-分子靶向治疗
报告人:Adrian Sacher
时间地点:14:42 - 14:52 8/07/2022 Location: Strauss 1/2
摘要号:OA03.05
Tepotinib in Patients with MET Exon 14 (METex14) Skipping NSCLC: Primary Analysis of the Confirmatory VISION Cohort C
Tepotinib 用于 MET 外显子 14 (METex14) 跳跃突变 NSCLC 患者:确认性 VISION 队列 C 的初步结果
专场:口头报告,转移性NSCLC-分子靶向治疗
报告人:Michael Thomas
时间地点:14:52 - 15:02 8/07/2022 Location: Strauss 1/2
摘要号:OA03.06
CodeBreaK 100/101: First Report of Safety/Efficacy of Sotorasib in Combination with Pembrolizumab or Atezolizumab in Advanced KRAS p.G12C NSCLC
CodeBreaK 100/101:Sotorasib 联合
专场:口头报告,转移性NSCLC-分子靶向治疗
报告人:Bob T. Li
时间地点:15:02 - 15:12 8/07/2022 Location: Strauss 1/2
摘要号:OA07.04
Overall Survival in Patients With Advanced NSCLC Receiving Taxane-Containing Regimen After Exposure to Immunotherapy and Platinum-Doublet
免疫治疗联合含铂治疗进展后再使用含紫杉烷方案治疗晚期 NSCLC 患者的OS结果
专场:口头报告,转移性NSCLC-姑息性化疗
报告人:Stephen V. Liu
时间地点:11:12 - 11:22 08/08/2022 Location: Strauss 1/2
摘要号:OA7.05
Gemcitabine Plus Platinum Chemotherapy Re-challenge in Metastatic Pulmonary Lymphoepithelioma-like Carcinoma
吉西他滨联合铂类化疗在转移性肺淋巴上皮瘤样癌中的“再挑战”结果
专场:口头报告,转移性NSCLC-姑息性化疗
报告人:Gavin Tin Chun Cheung
时间地点:11:22 - 11:32 08/08/2022 Location: Strauss 1/2
摘要号:OA07.06
Second Line Treatment Outcomes After Progression on Immunotherapy Plus Chemotherapy (IO-CT) In Advanced Non-small Cell Lung Cancer (aNSCLC)
晚期NSCLC 免疫治疗+化疗 (IO-CT) 进展后的二线治疗疗效分析
专场:口头报告,转移性NSCLC-姑息性化疗
报告人:Edouard Auclin
时间地点:11:32 - 11:42 08/08/2022 Location: Strauss 1/2
摘要号:OA11.05
Treatment Strategies Based on Different Oligoprogressive Patterns after Immunotherapy Resistance in Advanced NSCLC
晚期 NSCLC 免疫治疗耐药后基于不同寡进展模式的治疗策略
专场:口头报告,转移性NSCLC-寡转移性疾病
报告人:
时间地点:16:22 - 16:32 8/08/2022 Location: Strauss 1/2
摘要号:OA11.06
Sequencing of ctDNA Revealed Radiotherapeutic Efficacy and Prognosis in Non-small Cell Lung Cancer Patients with Brain Metastasis
ctDNA 测序揭示
专场:口头报告,转移性NSCLC-寡转移性疾病
报告人:董晓荣
时间地点:16:32 - 16:42 8/08/2022 Location: Strauss 1/2
摘要号:OA12.03
Phase 2 Study Analysis of Talazoparib (TALA) Plus Temozolomide (TMZ) for Extensive-Stage Small Cell Lung Cancer (ES-SCLC)
Talazoparib (TALA) +
专场:口头报告,SCLC和神经内分泌肿瘤
报告人:Jonathan Goldman
时间地点:16:02 - 16:12 8/08/2022 Location: Strauss 3
摘要号:OA12.04
Efficacy of Nivolumab and Temozolomide in Extensive Stage Small Cell Lung Cancer after Chemo-Immunotherapy: A Phase 2 Trial.
专场:口头报告,SCLC和神经内分泌肿瘤
报告人:Dwight H Owen
时间地点:16:12 - 16:22 8/08/2022 Location: Strauss 3
摘要号:OA12.05
Phase 1 Updated Exploration and First Expansion Data for DLL3-targeted T-cell Engager Tarlatamab in Small Cell Lung Cancer
靶向DLL3 T 细胞接合剂 Tarlatamab用于小细胞肺癌的第一阶段更新结果和首次扩展数据结果
专场:口头报告,SCLC和神经内分泌肿瘤
报告人:Hossein Borghaei
时间地点:16:22 - 16:32 8/08/2022 Location: Strauss 3
摘要号:OA12.06
First-Line Pembrolizumab or Placebo Combined With Etoposide and Platinum for ES-SCLC: KEYNOTE-604 Long-Term Follow-Up Results
一线帕博利珠单抗对比安慰剂联合
专场:口头报告,SCLC和神经内分泌肿瘤
报告人:Charles M Rudin
时间地点:16:32 - 16:42 8/08/2022 Location: Strauss 3
摘要号:OA15.03
Avelumab vs Chemotherapy for First-line Treatment of Advanced PD-L1+ NSCLC: Primary Analysis from JAVELIN Lung 100
Avelumab 对比化疗一线治疗晚期 PD-L1+ NSCLC:JAVELIN Lung 100 的初步分析
专场:口头报告,转移性NSCLC-免疫治疗
报告人:Martin Reck
时间地点:14:32 - 14:42 8/09/2022 Location: Strauss 1/2
摘要号:OA15.04
Association Between KRAS/STK11/KEAP1 Mutations and Outcomes in POSEIDON: Durvalumab ± Tremelimumab + Chemotherapy in mNSCLC
KRAS/STK11/KEAP1 突变与
专场:口头报告,转移性NSCLC-免疫治疗
报告人:Solange Peters
时间地点:14:42 - 14:52 8/09/2022Location: Strauss 1/2
摘要号:OA15.05
HUDSON: An Open-Label, Multi-Drug, Biomarker-Directed Phase 2 Study in NSCLC Patients Who Progressed on Anti-PD-(L)1 Therapy
HUDSON:一项关于 PD-(L)1单抗治疗进展 NSCLC 患者的开放标签、多药物、生物标志物指导的 2 期研究
专场:口头报告,转移性NSCLC-免疫治疗
报告人:Benjamin Besse
时间地点:14:52 - 15:02 8/09/2022Location: Strauss 1/2
摘要号:OA15.06
Pooled Analysis of Outcomes With Second-Course Pembrolizumab Across 5 Phase 3 Studies of Non-Small-Cell Lung Cancer
在针对NSCLC的 5 项III期研究中对第二疗程帕博利珠单抗进行汇总分析的结果
专场:口头报告,转移性NSCLC-免疫治疗
报告人:Delvys Rodriguez-Abreu
时间地点:15:02- 15:12 8/09/2022 Location: Strauss 1/2
摘要号:MA06.03
Pre-treatment ctDNA Levels Significantly Predicts of OS and PFS in NADIM II Trial
治疗前 ctDNA 水平显著预测 NADIM II 试验的 OS 和 PFS结果
专场:迷你口头报告,局部晚期NSCLC
报告人:Atocha Romero
时间地点:12:17 - 12:22 8/08/2022Location: Hall C8
摘要号:MA06.04
Phase II Study of Durvalumab Plus Concurrent Radiotherapy in Unresectable Locally Advanced NSCLC: DOLPHIN Study (WJOG11619L)
度伐利尤单抗+同步放疗在不可切除的局部晚期 NSCLC 中的 II 期研究:DOLPHIN 研究 (WJOG11619L)
专场:迷你口头报告,局部晚期NSCLC
报告人:Motoko Tachihara
时间地点:12:22 - 12:27 8/08/2022 Location: Hall C8
摘要号:MA06.05
Consolidation Nivolumab and Ipilimumab or Nivolumab Alone Following Concurrent Chemoradiation for Patients with Unresectable Stage III NSCLC
不可切除的 III 期 NSCLC 患者在同步放化疗后使用纳武利尤单抗+
专场:迷你口头报告,局部晚期NSCLC
报告人:Greg Andrew Durm
时间地点:12:27 - 12:32 8/08/2022 Location: Hall C8
摘要号:MA07.04
Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy in Relapsed/Refractory EGFR-mutant NSCLC
Amivantamab + Lazertinib 联合铂类化疗治疗复发/难治性 EGFR 突变 NSCLC
专场:迷你口头报告,转移性NSCLC-分子靶向治疗
报告人:Melina Elpi Marmarelis
时间地点:12:22 - 12:27 8/08/2022 Location: Strauss 1/2
摘要号:MA07.05
Phase 1b/2 Study of Combined HER Inhibition in Refractory EGFR-mutated Metastatic Non-small Cell Lung Cancer (NSCLC)
联合 HER 抑制在难治性 EGFR 突变的转移性NSCLC 中的结果:一项 1b/2 期研究
专场:迷你口头报告,转移性NSCLC-分子靶向治疗
报告人:Jonathan Goldman
时间地点:12:27 - 12:32 8/08/2022 Location: Strauss 1/2
摘要号:MA07.08
JIN-A02, a Highly Effective 4th Generation EGFR-TKI, Targeting EGFR C797S Triple Mutation in NSCLC
JIN-A02(一种高效的第 4 代 EGFR-TKI)在 NSCLC突变、 EGFR C797S 三重突变中的疗效
专场:迷你口头报告,转移性NSCLC-分子靶向治疗
报告人:Byoung Chul Cho
时间地点:12:47 - 12:52 8/08/2022 Location: Strauss 1/2
摘要号:MA07.09
BBT-176, a 4th generation EGFR TKI, for Progressed NSCLC after EGFR TKI Therapy: PK, Safety and Efficacy from Phase 1 Study
BBT-176(一种第 4 代 EGFR TKI)用于 EGFR TKI 治疗后进展的 NSCLC的疗效:1 期研究的 PK、安全性和有效性 。
专场:迷你口头报告,转移性NSCLC-分子靶向治疗
报告人:Sun Min Lim
时间地点:12:52- 12:57 8/08/2022 Location: Strauss 1/2
摘要号:MA09.04
First-line PD-1 Inhibitors and Chemotherapy Combined with or without Radiotherapy in Advanced Non-small-cell Lung Cancer
一线 PD-1 抑制剂和化疗联合或不联合放疗治疗晚期NSCLC
专场:迷你口头报告,姑息性放疗
报告人:董晓荣
时间地点:14:52 - 14:57 8/08/2022 Location: Strauss 1/2
摘要号:MA09.08
Radiotherapy Improves Outcomes to Immunotherapy in Patients with Stage III and IV NSCLC
放疗改善 III 期和 IV 期 NSCLC 患者的免疫治疗结果
专场:迷你口头报告,姑息性放疗
报告人:Haihua Yang
时间地点:15:17 - 15:22 8/08/2022 Location: Strauss 1/2
摘要号:MA13.03
Integrated Efficacy and Safety of Brigatinib Following Alectinib Treatment in the ALTA-2 and J-ALTA Studies
ALTA-2 和 J-ALTA 研究中
专场:迷你口头报告,转移性NSCLC-分子靶向治疗
报告人:Sai-Hong Ignatius Ou
时间地点:12:02 - 12:07 8/09/2022 Location: Strauss 1/2
摘要号:MA13.04
Entrectinib in Patients with ROS1 Fusion-Positive (ROS1-fp) NSCLC: Updated Efficacy and Safety Analysis
恩曲替尼治疗 ROS1 融合阳性 (ROS1-fp) NSCLC 患者:更新的疗效和安全性分析
专场:迷你口头报告,转移性NSCLC-分子靶向治疗
报告人:Yun Fan
时间地点:12:07 – 12:12 8/09/2022 Location: Strauss 1/2
摘要号:MA13.07
TROPION-Lung02: Initial Results for Datopotamab Deruxtecan Plus Pembrolizumab and Platinum Chemotherapy in Advanced NSCLC
TROPION-Lung02:Datopotamab Deruxtecan + 帕博利珠单抗和铂类化疗在晚期 NSCLC 中的初步结果
专场:迷你口头报告,转移性NSCLC-分子靶向治疗
报告人:Benjamin Levy
时间地点:12:27 - 12:32 8/09/2022 Location: Strauss 1/2
摘要号:MA14.05
A Double-blind Phase III Trial of Denosumab Biosimilar QL1206 vs Denosumab in Bone Metastatic Tumor: Lung Cancer Cohort Data
地舒单抗生物仿制药 QL1206 对比地舒单抗在骨转移性肿瘤中的双盲 III 期试验:肺癌队列数据
专场:迷你口头报告,姑息性治疗和支持治疗
报告人:Yan Huang
时间地点:14:42 - 14:47 8/09/2022 Location: Strauss 3
摘要号:EP05.02-006
Neoadjuvant DS-8201 for Stage III Non-small Cell Lung Cancer with HER2 20ins
新辅助 DS-8201在HER2 20ins III 期NSCLC患者中的疗效
类型:壁报展示
专场:局部晚期NSCLC-新辅助和辅助治疗
报告人:Huizhao Hong
时间:09:45 - 18:00 8/07/2022
摘要号:EP05.02-008
Phase II Trial of Neoadjuvant Icotinib Plus Chemotherapy for Stage II-IIIB EGFR-mutant Non-small-Cell Lung Cancer
新辅助埃克替尼加化疗治疗 II-IIIB 期 EGFR 突变非小细胞肺癌的 II 期试验
类型:壁报展示专场:局部晚期NSCLC-新辅助和辅助治疗
报告人:Fang-Liang Lu
时间:09:45 - 18:00 8/07/2022
摘要号:EP05.02-009
Aumolertinib Versus Erlotinib/Chemotherapy for Neoadjuvant Treatment of Stage IIIA EGFR-mutant NSCLC (ANSWER)
类型:壁报展示专场:局部晚期NSCLC-新辅助和辅助治疗
报告人:Wenhua Liang
时间:09:45 - 18:00 8/07/2022
摘要号:EP05.02-011
Phase II Trial of Neoadjuvant Tislelizumab with Chemotherapy for Resectable Stage IIB-III Non-small Cell Lung Cancer
新辅助
类型:壁报展示专场:局部晚期NSCLC-新辅助和辅助治疗
报告人:Yao-Bin Lin
时间:09:45 - 18:00 8/07/2022
摘要号:EP05.02-014
Neoadjuvant Toripalimab Combination in Patients with Stage IIB-IIIB NSCLC: A Single-Arm, Phase 2 Trial (Renaissance Study)
新辅助联合 Toripalimab在 IIB-IIIB 期 NSCLC 患者中的疗效:单臂、2 期试验
类型:壁报展示
专场:局部晚期NSCLC-新辅助和辅助治疗
报告人:Shi Yan
时间:09:45 - 18:00 8/07/2022
摘要号:EP08.01-001
Update Analysis of Sintilimab With Two Cycles Chemotherapy for Untreated Advanced Squamous Non-small-Cell Lung Cancer
初治晚期鳞状非小细胞肺癌接受两周期化疗+
类型:壁报展示
专场:转移性NSCLC-免疫治疗
报告人:Huijuan Wang
时间:09:45 - 18:00 8/07/2022
摘要号:EP08.01-014
Tislelizumab versus Docetaxel in Previously Treated Advanced Non-Small Cell Lung Cancer: Final Analysis of RATIONALE-303
替雷利珠单抗对比多西他赛用于经治晚期NSCLC:RATIONALE-303 的最终分析
类型:壁报展示专
场:转移性NSCLC-免疫治疗
报告人:
时间:09:45 - 18:00 8/07/2022
摘要号:EP08.01-032
Sintilimab in Combination with Anlotinib in NSCLC Patients with Uncommon EGFR Mutations: A Phase II, Single-arm, Prospective Study
信迪利单抗+
类型:壁报展示
专场:转移性NSCLC-免疫治疗
报告人:Yun Fan
时间:09:45 - 18:00 8/07/2022
摘要号:EP08.01-033
ML40471: Preliminary Analysis of Atezolizumab in Previously Treated Patients With Locally Advanced or Metastatic NSCLC
ML40471:阿替利珠单抗在经治局部晚期或转移性 NSCLC 患者中的初步分析
类型:壁报展示
专场:转移性NSCLC-免疫治疗
报告人:Yun Fan
时间:09:45 - 18:00 8/07/2022
摘要号:EP08.01-042
NEPTUNE China Cohort: First-Line Durvalumab + Tremelimumab versus Chemotherapy in Chinese Patients with Metastatic NSCLC
NEPTUNE 中国队列:一线度伐利尤单抗 + Tremelimumab 与化疗用于中国转移性 NSCLC 患者的研究
类型:壁报展示
专场:转移性NSCLC-免疫治疗
报告人:
时间:09:45 - 18:00 8/07/2022
摘要号:EP08.01-070
Safety and Efficacy of Sitravatinib + Tislelizumab in Patients with PD-L1+, Locally Advanced/Metastatic, Squamous NSCLC
Sitravatinib + 替雷利珠单抗在 PD-L1+、局部晚期/转移性、鳞状 NSCLC 患者中的安全性和有效性
类型:壁报展示
专场:转移性NSCLC-免疫治疗
报告人:赵军
时间:09:45 - 18:00 8/07/2022
摘要号:EP08.01-071
Safety and Efficacy of Sitravatinib + Tislelizumab in Patients with PD-L1+, Locally Advanced/Metastatic, Non-Squamous NSCLC
Sitravatinib +替雷利珠单抗在 PD-L1+、局部晚期/转移性、非鳞状 NSCLC 患者中的安全性和有效性
类型:壁报展示
专场:转移性NSCLC-免疫治疗报告人:赵军
时间:09:45 - 18:00 8/07/2022
摘要号:EP08.01-094
A Phase II Study of Camrelizumab combined with Apatinib and Albumin Paclitaxel in Advanced Non-squamous NSCLC (CAPAP-lung)
类型:壁报展示
专场:转移性NSCLC-免疫治疗
报告人:Lin Wu
时间:09:45 - 18:00 8/07/2022
摘要号:EP08.01-102
Anlotinib Combined with PD-1 Inhibitors May Benefit Advanced Non-small Cell Lung Cancer Patients After Failure of EGFR-TKI Therapy
安罗替尼联合 PD-1 抑制剂可能使 EGFR-TKI 治疗失败后的晚期NSCLC患者受益
类型:壁报展示专场:转移性NSCLC-免疫治疗报告人:Lian Yu时间:09:45 - 18:00 8/07/2022
摘要号:EP08.02-001
Concurrent Aumolertinib and Cerebral Radiotherapy as First-Line Treatment for EGFR Mutated Non-small Cell Lung Cancer with Brain Metastases
阿美替尼和脑放疗同时用于 EGFR 突变的脑转移NSCLC的一线治疗的结果
类型:壁报展示
专场:转移性NSCLC-分子靶向治疗
报告人:Jie Tan
时间:09:45 - 18:00 8/07/2022
摘要号:EP08.02-009
Progression Pattern, Resistance Mechanism and Subsequent Therapy for ALK Positive NSCLC in the Era of Second—Generation ALK—TKIs
第二代 ALK-TKI 时代 ALK 阳性 NSCLC 的进展模式、耐药机制和后续治疗
类型:壁报展示专场:转移性NSCLC-分子靶向治疗
报告人:Zihua Zou
时间:09:45 - 18:00 8/07/2022
摘要号:EP08.02-052
Safety and Efficacy of Dabrafenib Plus Trametinib in Chinese Patients With BRAF V600E- Mutation Positive Metastatic NSCLC
类型:壁报展示专场:转移性NSCLC-分子靶向治疗
报告人:Yun Fan时间:09:45 - 18:00 8/07/2022
摘要号:EP08.02-063
SANOVO: A Phase 3 Study of Savolitinib or Placebo in Combination with Osimertinib in Patients with EGFR-mutant and MET Overexpressed NSCLC
SANOVO:赛沃替尼或安慰剂联合
类型:壁报展示
专场:转移性NSCLC-分子靶向治疗
报告人:周清
时间:09:45 - 18:00 8/07/2022
摘要号:EP08.02-138
SAFFRON: Ph3 Savolitinib + Osimertinib vs Chemotherapy in EGFRm NSCLC with MET Overexpression/Amplification Post-Osimertinib
SAFFRON:赛沃替尼+ 奥希替尼对比化疗用于奥希替尼治疗进展、MET 过表达/扩增 EGFR突变 NSCLC 患者的疗效
类型:壁报展示
专场:转移性NSCLC-分子靶向治疗
报告人:陆舜
时间:09:45 - 18:00 8/07/2022